Episode 44 – Multi-system Inflammatory Syndrome in Children (MIS-C): An Interview with Dr. Ilene Claudius and Dr. Mohsen Saidinejad

 

EMplify June 2020

Multi-system Inflammatory Syndrome in Children (MIS-C) with COVID-19: An Interview with Dr. Ilene Claudius and Dr. Mohsen Saidinejad.

  • What is it and when did we discover it as an entity?
  • Have either of you treated anyone with the disease?
  • Discussion of different cohorts of patients with MIS-C.
  • Definition of MIS-C.
  • Shock: cardiogenic and distributive shock presentations.
  • Fever, is 4 days required?
  • Discussion of where in the COVID-19 illness MIS-C occurs.
  • Is clinical shock a requirement?
  • Screening criteria (labs) and the Children’s Hospital Of Philadelphia pathway.
  • What is available as treatment?
    • A discussion of IVIG
    • Steroids
    • Cytokine blockers
    • Remdesivir
  • Why IVIG?
  • Complications of the disease.
  • Why are there more cases in New York?
  • How has MIS-C changed your practice of testing children?
  • Is there utility in testing for COVID-19 infection or antibodies in these cases?

 

Resources:
EB Medicine Novel 2019 Coronavirus SARS-CoV-2 (COVID-19): An Updated Overview for Emergency Clinicians

EB Medicine COVID-19: The Impact on Pediatric Emergency Care

Children’s Hospital of Philadelphia Clinical Pathway for MIS-C.

Have questions or comments on the podcast? Leave us a voicemail at 678-336-8466, ext 128 or write us at emplify@ebmedicine.net .

 

Last Updated on April 29, 2022

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