Angioedema is a histamine- or bradykinin-mediated response that can be acquired, hereditary, or idiopathic. Manifestations include nonpitting edema of the subcutaneous layer of the skin or submucosal layers of the respiratory or gastrointestinal tracts. While acute presentations are typically transient and localized, angioedema can result in acute airway compromise, requiring immediate stabilization.
Our recent issue Angioedema in the Emergency Department: An Evidence-Based Update assesses current literature on the etiology and management of angioedema in the emergency department.
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Here are a few key points:
- Angioedema can be acute or chronic, acquired or hereditary.
- Angioedema is broadly classified into 3 categories: (1) histamine-mediated, (2) bradykinin-mediated, and (3) idiopathic.
- The patient’s symptoms will help distinguish histamine- and bradykinin-mediated angioedema.
Read the full issue and earn 4 CME credits!
Last Updated on January 25, 2023