Take a deeper dive into our peer-reviewed emergency medicine content with the EMplify podcast. Join hosts Sam Ashoo, MD and T.R. Eckler, MD for educational, conversational reviews of current evidence guaranteed to help you make your best clinical decisions. Each high-yield episode gives you practical, time-tested guidance from practicing emergency medicine clinicians and subject-matter experts. Listen and learn!
In this episode, Sam Ashoo, MD and Dr. T.R. Eckler, MD discuss the June 2026 Emergency Medicine Practice article, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management in the Emergency Department.
- 0:17 – Intro & sponsor promo
- 1:09 – Episode introduction
- 4:03 – Definitions: SJS vs. TEN vs. “overlap” by body surface area
- 6:12 – Pathophysiology
- 9:52 – Incidence and rarity of the disease
- 10:53 – Differential diagnosis & clinical presentation clues
- 12:08 – Prehospital care & fluid resuscitation considerations
- 13:47 – ED history-taking: medications, infections, rash progression
- 14:47 – Physical exam findings
- 16:46 – Diagnostic studies
- 18:12 – Scoring systems: SCORTEN and ABCD-10
- 20:50 – Treatment goals
- 23:57 – Wound care principles
- 24:43 – Mechanical ventilation risk factors
- 26:02 – Other possible therapies
- 27:50 – Specialty consults & special populations
- 29:06 – Ophthalmologic treatment
- 31:17 – HIV patients and elevated risk
- 31:55 – Emerging therapies & AI-based diagnostic tools
- 32:57 – Five key clinical takeaways
- 34:37 – Closing remarks & sponsor sign-off
Subscribers, take the CME test here.
Emergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net
In this episode, Sam Ashoo, MD and Dr. T.R. Eckler, MD discuss the July 2026 Emergency Medicine Practice article, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management in the Emergency Department.
- 0:17 – Intro & sponsor promo
- 1:09 – Episode introduction
- 4:03 – Definitions: SJS vs. TEN vs. “overlap” by body surface area
- 6:12 – Pathophysiology
- 9:52 – Incidence and rarity of the disease
- 10:53 – Differential diagnosis & clinical presentation clues
- 12:08 – Prehospital care & fluid resuscitation considerations
- 13:47 – ED history-taking: medications, infections, rash progression
- 14:47 – Physical exam findings
- 16:46 – Diagnostic studies
- 18:12 – Scoring systems: SCORTEN and ABCD-10
- 20:50 – Treatment goals
- 23:57 – Wound care principles
- 24:43 – Mechanical ventilation risk factors
- 26:02 – Other possible therapies
- 27:50 – Specialty consults & special populations
- 29:06 – Ophthalmologic treatment
- 31:17 – HIV patients and elevated risk
- 31:55 – Emerging therapies & AI-based diagnostic tools
- 32:57 – Five key clinical takeaways
- 34:37 – Closing remarks & sponsor sign-off
Subscribers, take the CME test here.
Emergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net
Sam Ashoo, MD, FACEP, is board certified in emergency medicine and clinical informatics. He serves as EB Medicine’s editor-in-chief of interactive clinical pathways and FOAMEd blog, and host of EB Medicine’s EMplify podcast. Follow him below for more…
