Take a deeper dive into our peer-reviewed emergency medicine content with the EMplify podcast. Join hosts Sam Ashoo, MD and T.R. Eckler, MD for educational, conversational reviews of current evidence guaranteed to help you make your best clinical decisions. Each high-yield episode gives you practical, time-tested guidance from practicing emergency medicine clinicians and subject-matter experts. Listen and learn!
In this episode, Sam Ashoo, MD, Dr. Christopher Baugh, MD, MBA, and Dr. Xin Qi, MD, discuss the October 2026 Emergency Medicine Practice article, Antithrombotic-Associated Bleeding: Management in the Emergency Department.
1:18 — Guest introductions
1:58 — Why the authors chose this topic
3:11 — Epidemiology
4:27 — Why DOACs over warfarin
5:15 — Bleeding trends
6:55 — Overlapping antithrombotic regimens
8:09 — Reversibility of agents
9:38 — Bedside priorities
11:31 — Bleeding patterns by drug class & three groups
13:50 — Antithrombotics & traumatic bleeding risk
14:26 — Pre-hospital considerations
16:09 — Indications for antithrombotic use & risk of reversing
17:54 — Gray-area decisions
19:02 — Initial resuscitation
20:08 — Blood product ratios
21:24 — PATCH trial
22:04 — TXA evidence
23:36 — GI bleed adjuncts
24:31 — Critical site bleeds
27:20 — Endoscopy timing
30:00 — Reversal agents
32:50 — Idarucizumab for dabigatran
33:54 — Antiplatelet reversal
36:15 — Warfarin reversal
38:36 — Protamine for heparin/LMWH
39:37 — Fibrinolytic reversal
40:14 — Pre-procedural antithrombotic management
42:39 — Emerging labs
43:50 — Wrap-up & closing promo
Subscribers, take the CME test here.
Emergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net
In this episode, Sam Ashoo, MD, Dr. Christopher Baugh, MD, MBA, and Dr. Xin Qi, MD, discuss the October 2026 Emergency Medicine Practice article, Antithrombotic-Associated Bleeding: Management in the Emergency Department.
- 1:18 — Guest introductions
- 1:58 — Why the authors chose this topic
- 3:11 — Epidemiology
- 4:27 — Why DOACs over warfarin
- 5:15 — Bleeding trends
- 6:55 — Overlapping antithrombotic regimens
- 8:09 — Reversibility of agents
- 9:38 — Bedside priorities
- 11:31 — Bleeding patterns by drug class & three groups
- 13:50 — Antithrombotics & traumatic bleeding risk
- 14:26 — Pre-hospital considerations
- 16:09 — Indications for antithrombotic use & risk of reversing
- 17:54 — Gray-area decisions
- 19:02 — Initial resuscitation
- 20:08 — Blood product ratios
- 21:24 — PATCH trial
- 22:04 — TXA evidence
- 23:36 — GI bleed adjuncts
- 24:31 — Critical site bleeds
- 27:20 — Endoscopy timing
- 30:00 — Reversal agents
- 32:50 — Idarucizumab for dabigatran
- 33:54 — Antiplatelet reversal
- 36:15 — Warfarin reversal
- 38:36 — Protamine for heparin/LMWH
- 39:37 — Fibrinolytic reversal
- 40:14 — Pre-procedural antithrombotic management
- 42:39 — Emerging labs
- 43:50 — Wrap-up & closing promo
Subscribers, take the CME test here.
Emergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net
Sam Ashoo, MD, FACEP, is board certified in emergency medicine and clinical informatics. He serves as EB Medicine’s editor-in-chief of interactive clinical pathways and FOAMEd blog, and host of EB Medicine’s EMplify podcast. Follow him below for more…
