Test Your Knowledge of Caring for Transgender and Gender-Diverse Patients in the Urgent Care Setting (Postscript 2 of 2)

Evidence-Based Urgent Care Postscript
Caring for Transgender and Gender-Diverse Patients in the Urgent Care Setting | October 2026

A 21-year-old transgender man presents to urgent care with 2 days of dysuria, urinary frequency, and suprapubic discomfort. His chart lists male gender, and the medical assistant initially documents “male patient with possible prostatitis.” His vital signs are temperature, 98.8°F; heart rate, 88 beats/min; blood pressure, 118/72 mm Hg; respiratory rate, 14 breaths/min; and oxygen saturation, 100% on room air. He appears comfortable and nontoxic. Examination reveals mild suprapubic tenderness without guarding or rebound; there is no costovertebral angle tenderness. During a private, anatomy-based history, the patient shares that he has a vagina and uterus, has not had genital surgery, and recently had receptive vaginal sex with a new partner. He is taking testosterone but is not using contraception. Urinalysis shows leukocyte esterase and nitrites.

Which of the following is the most appropriate next step?

  1. Treat for prostatitis because the patient’s chart lists male gender.
  2. Avoid asking about anatomy or sexual practices because these questions may be intrusive.
  3. Treat for uncomplicated urinary tract infection and consider pregnancy and STI testing based on anatomy and exposure.
  4. Refer the patient to the emergency department because all genitourinary symptoms in TGD patients require higher-level care.

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