2009 Sickle Cell Foundation of Georgia: Jackie George, Beverly Sinclair This digitally-colorized scanning electron micrograph (SEM) revealed some of the comparative ultrastructural morphology between normal red blood cells (RBCs), and a sickle cell RBC (left) found in a blood specimen of an 18 year old female patient with sickle cell anemia, (HbSS); People who have this form of sickle cell disease inherit two sickle cell genes (“S”), one from each parent. This is commonly called “sickle cell anemia”, and is usually the most severe form of the disease. Sickle cell disease is a group of inherited red blood cell disorders. Healthy red blood cells are round, and they move through small blood vessels to carry oxygen to all parts of the body. In sickle cell disease, the red blood cells become hard and sticky and look like a C-shaped farm tool called a ?sickle?. The sickle cells die early, which causes a constant shortage of red blood cells. Also, when they travel through small blood vessels, they get stuck and clog the blood flow. This can cause pain and other serious problems.
EMplify Podcast

Sickle Cell Disease in the ED

August 14, 2024
Sam Ashoo, MD
Sickle Cell Disease in the ED
Sickle Cell Disease in the ED

In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the August 2024 Emergency Medicine Practice article, Emergency Department Management of Patients With Sickle Cell Disease

  • Epidemiology
    • Common Presentation of Sickle Cell Disease in the ED
    • Screening and Diagnosis Differences
    • Epidemiology: 200,000 ED Visits Annually, 85% for Pain
  • Pathophysiology
    • Life Expectancy and Complications
    • Vado-Occlusive Crises and Pathophysiology
    • Sequestration Crisis in Sickle Cell Patients
    • Acute Chest Syndrome and Priapism
  • Clinical Management
    • Treatment Advocacy and Pain Management
    • Patient History and Examination Importance
    • Imaging Recommendations
    • Laboratory Studies and Findings
    • Emergency Department Care Protocols
  • Advanced Treatment Options
    • Intravenous (IV) Fluids Guideline
    • Management of Priapism
    • Role of Exchange Transfusion
    • Acute Chest Syndrome Details
    • Approach in Rural and Critical Access Hospitals
  • Special Populations
    • Pregnant Patients with Sickle Cell Disease
    • Increased Risks and Complication Management
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