Neonatal Hyperbilirubinemia – Clinical Pathway

Hyperbilirubinemia is one the most common reasons for emergency department visits for the neonate. Most cases of unconjugated hyperbilirubinemia are benign. Although rare, unrecognized or untreated pathologic unconjugated hyperbilirubinemia can lead to the development of acute bilirubin encephalopathy and, ultimately, kernicterus. Our recent issue Neonatal Hyperbilirubinemia: Recommendations for Diagnosis and Management in the Emergency Department reviews the emergency department evaluation and management of neonatal hyperbilirubinemia and discusses how to recognize acute bilirubin encephalopathy, with the goal of preventing kernicterus. 

To help you with the decision-making process, we’ve created the clinical pathway below for managing neonatal hyperbilirubinemia in the ED.

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Last Updated on June 10, 2022

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